Physiology and Pathology of Channels in the Nervous System
Gebundenes Buch

Physiology and Pathology of Channels in the Nervous System

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Single membrane channels are created through combination of two distinct membrane protein families, pannexins and connexins. These channels function as aqueous pores absorbent to small molecules and ions, to permit the diffusional interchange between the intracellular and extracellular environments. Ion fluxes across the plasma membrane in all mammalian cells are controlled by these specific membrane proteins. The channels create functional oligomeric complexes by interacting with ancillary proteins that contribute to health maintenance and cellular homeostasis. Membrane channels having varied...