Physiologically Based Pharmacokinetic Modeling

Physiologically Based Pharmacokinetic Modeling

Science and Applications

By Micaela B. Reddy, Raymond S. H. Yang, Melvin E. Andersen et al.
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A definitive, single source of information on PBPK modelingPhysiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling purposes so users can quickly access information, this is the first comprehensive reference of its kind.This book presents an overview of the underlying principles of PBPK model development. Then it provides a compendium of PBPK modeling information, including historical development, specific modeling chall...