Pharmaceutical Product Development of Verapamil HCL by SD Technique
Pharmaceutical Product Development of Verapamil Hydrochloride for Improved Bioavailability by Solid Dispersion Technique
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Solid dispersions have attracted considerable interest as an efficient means of improving the dissolution rate and hence the bioavailability of a range of hydrophobic drugs. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of carrier and methods of physicochemical characterization, along with an insight into the molecular arrangement of drugs in solid dispersions are also discussed. Finally, an in-depth rationale for limited commercialization of solid dispersions and recent revival has been considered.
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