Penciclovir
Guanine, Antiviral Drug, Herpesviridae, Famciclovir
Herausgegeben: Aoide, Noelene
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Penciclovir (INN) (pronounced /p n sa kl v r/) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. Because penciclovir is absorbed poorly when given orally (by mouth) it is used more as a topical treatment, and is the active ingredient in the cold sore medications Denavir (NDC 0135-0315-52), Vectavir and Fenistil. Famciclovir is a prodrug of penciclovir with improved oral bioavailability.
