Gebundenes Buch

Pancreatic B Cell Biology in Health and Disease

Beschreibung

Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more.

Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease.

Autor

Izortze Santin is assistant professor and researcher in the Department of Biochemistry and Molecular Biology of the University of the Basque Country (Leioa, Spain). She obtained her PhD in Genetics of autoimmune diseases in 2004, and then, she moved to the ULB Center for Diabetes Research (Brussels, Belgium) where she completed her formation in diabetes with functional studies in in vitro models of pancreatic beta cell and in vivo models of type 1 diabetes. Izortze Santin is best known for major experimental and conceptual contributions to the research of pancreatic beta cell dysfunction in type 1 diabetes. Indeed, her work has highlighted the implication of type 1 diabetes candidate genes in the regulation of several pathways related to pancreatic beta cell inflammation and death.
Currently her main research line aims to characterize how T1D genes (coding and non-coding) and viral infections interact to trigger the autoimmune destruction of pancreatic beta cells in type 1 dia

betes. To this aim, she has several ongoing funded projects related to type 1 diabetes pathogenesis, in which the study of pancreatic beta cell acquired a central role.

Produktdetails

• International Review of Cell and Molecular Biology Volume 359
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: S1937-6448(21)X0003-2
• Englisch
• Abmessung: 22mm x 152mm x 229mm
• Gewicht: 790g
• ISBN-13: 9780128237557
• Artikelnr.: 67579015