Pain: Mechanisms of signal processing in neuronal spinal synapses
Sônia Santos
Broschiertes Buch

Pain: Mechanisms of signal processing in neuronal spinal synapses

Physiological characteristics and functional synaptic organization of spinal neurons involved in pain. A new view.

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Spinal substantia gelatinosa (SG) is an important element in the system of antinociception. However, little is known about major types of ion channels specifically expressed in SG neurons as well as their synaptic connections, forms of spontaneous and induced plasticity and the types of neurons serving as specific postsynaptic targets for opioid action within this region. To better understand how nociceptive information is processed within the superficial dorsal horn, a novel approach was implemented. This work was carried out for almost a decade and became a reference in the area. This functi...