Osteoporosis, the Immune System and Genetics

Osteoporosis, the Immune System and Genetics

A new approach to an old acquaintance

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Osteoporosis is a degenerative, multifactorial osteometabolic disease characterized by a reduction in bone mineral density and deterioration of tissue microarchitecture. Of the various systemic and local factors involved in the etiopathogenesis of the disease, the association between components of the immune system and the genetic background has been shown to be key in maintaining bone tissue homeostasis. As a multifactorial disease, it is essential that its main causes are identified early, thus preventing the progression of the disease. Cytokines are recognized as participating in this homeo...