Osteoimmunology
Broschiertes Buch

Osteoimmunology

Interactions of the Immune and skeletal systems II

Herausgegeben: Choi, Yongwon
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It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune...