Nicolaou Taxol Total Synthesis
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of Taxol. This organic synthesis was included in Nicolaou''s book, ''Classics in Total Synthesis''. Taxol is an important drug in the treatment of cancer but also expensive because the compound is harvested from a scarce resource, namely the pacific yew. This synthetic route to Taxol is one of several; other groups have presented their own solutions, nota...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Nicolaou Taxol total synthesis, published by K. C. Nicolaou and his group in 1994 concerns the total synthesis of Taxol. This organic synthesis was included in Nicolaou''s book, ''Classics in Total Synthesis''. Taxol is an important drug in the treatment of cancer but also expensive because the compound is harvested from a scarce resource, namely the pacific yew. This synthetic route to Taxol is one of several; other groups have presented their own solutions, notably the group of Holton with a linear synthesis starting from borneol, the Samuel Danishefsky group starting from the Wieland-Miescher ketone and the Wender group from pinene.
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