ext-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies.
ext-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies.
Stuart M. Brown is an Associate Professor at the NYU Center for Health Informatics and Bioinformatics. He leads a consulting group focused on Sequencing Informatics and teaches graduate Bioinformatics courses. His current research includes de novo sequencing/assembly/annotation of interesting genomes, RNA-seq gene expression studies, motif analysis of gene regulatory domains, and data management for integrative genomics projects. He is the author of Next-Generation DNA Sequencing Informatics (2012, 2015) and Essentials of Medical Genomics (2008). He received his PhD. in molecular biology from Cornell University in 1992 and his BS in Botany from the University of Michigan in 1983.
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