New Piperazine Derivatives: Biologic and Spectroscopic Study

New Piperazine Derivatives: Biologic and Spectroscopic Study

A new piperazine derivatives were synthesized. All compounds were characterized by NMR, FT-IR, Mass spectral data

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A new piperazine derivatives: 2,2¿-(piperazine-1,4-diyl)bis(N¿-((Z)-2,4-dihydroxybenzylidene)acetohydrazide), 2.2¿-(piperazine-1,4-diyl)bis (N¿-((Z)-2-hydroxy-4-methoxybenzylidene)acetohydrazide) and 2.2¿-(piperazine-1,4-diyl) bis N¿-((Z)-1-(2-hydroxynaphthalen-1-yl) ethylidene) aceto hydrazide) were synthesized. The characterization of all compounds was characterized by NMR, FT-IR, Mass spectral data and elemental analysis. 1H and 13C shielding tensors of all compounds were calculated with GIAO/DFT/B3LYP/6-31 G(d) methods in DMSO. Molecular electrostatic potential surface and frontier o...