Neutrophilic Dermatoses: An Issue of Dermatologic Clinics
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Neutrophils are a type of white blood cell that plays a critical role in the immune systems, particularly in defending the body against infections. Neutrophilic dermatoses refer to a group of inflammatory skin conditions characterized by the predominant presence of neutrophils in the affected tissues. These conditions are marked by a rapid onset of skin lesions, which can include pustules, plaques, nodules and ulcers. Common types include pyoderma gangrenosum, Sweet's syndrome (acute febrile neutrophilic dermatosis), and neutrophilic eccrine hidradenitis. The exact cause of neutrophilic dermat...
Neutrophils are a type of white blood cell that plays a critical role in the immune systems, particularly in defending the body against infections. Neutrophilic dermatoses refer to a group of inflammatory skin conditions characterized by the predominant presence of neutrophils in the affected tissues. These conditions are marked by a rapid onset of skin lesions, which can include pustules, plaques, nodules and ulcers. Common types include pyoderma gangrenosum, Sweet's syndrome (acute febrile neutrophilic dermatosis), and neutrophilic eccrine hidradenitis. The exact cause of neutrophilic dermatoses is not fully understood but is thought to involve dysregulation of the immune system leading to an excessive accumulation of neutrophils in the skin. Diagnosis typically involves clinical evaluation, skin biopsy, and exclusion of other potential causes of similar symptoms. Treatment varies depending on the specific condition and severity but often includes systemic corticosteroids, immunosuppressants, and sometimes biologic agents targeting specific immune pathways. Management may require a multidisciplinary approach involving dermatologists and rheumatologists to achieve effective control of symptoms and prevent complications. This book unravels the recent studies in the field of neutrophilic dermatoses. Most of the topics introduced in this book cover new techniques and treatment methods. This book will prove to be immensely beneficial to students and researchers in this field.
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