Nano-aggregate of Block Copolymers in Aqueous Solutions
Anil Khanal
Broschiertes Buch

Nano-aggregate of Block Copolymers in Aqueous Solutions

Incorporation and Release of Anionic Drugs in Polymeric Micelles

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When ionic anticancer drugs are used without drug delivery systems, they are absorbed in the entire body. This decreases the effectiveness of the drugs. In order to circumvent these demerits, micelles of AB and ABA diblock copolymer are used for the delivery of ionic drugs. But, most of these micelles get collapsed in the blood stream. Hence, these micelles are not effective for the delivery of ionic drugs. Hence, this book describes extensive research works on the frozen micelles based on the ABC triblock copolymers. This frozen micelle does not collapse immediately even it is diluted extreme...