Myocardial Tissue Engineering

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This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. It focuses on myocardial cell source, cardiac cells differentiated from embryonic stem (ES)/ induced pluripotent stem (iPS) cells. Several chapters highlight innovative technologies developed to overcome the vascularization problem. Remarkable results obtained in the past and the present and challenges for the future in myocardial tissue engineering research field are...

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Tatsuya Shimizu is a professor at the Institute of Advanced Biomedical Engineering and Science (ABMES), Tokyo Women's Medical University, Japan. He received his PhD in medicine from Tokyo University, Japan. His areas of expertise are myocardial tissue engineering based on cell sheet technology, neovascularization in myocardial tissue grafts for scaling-up, and tissue factory fabrication for industrialization of regenerative medicine. He has 96 publications to his credit. He has received the Takagi Award, Intelligent Materials and Systems Forum (2001); best poster award, 5th International Meeting of Tissue Engineering Society (2002); Young Investigator's Award, the Japanese Circulation Society (2002); The 2003 award of the Medical Association of Tokyo Women's Medical University; Best Oral communication Award, Annual TERMIS-EU Meeting (2006); The Award of Cardiovascular Regenerative Medicine, the Japanese Circulation Society (2007); The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (Research Category) (2009); The 7th Monozukuri cooperation Award, Nikkan Kogyo Shimbun Ltd. (2012); and Japan Heart Foundation Satoh Memorial Award, The Japanese Circulation Society (2014). His current research interests are vascularization and heart engineering. Katsuhisa Matsuura is an associate professor at ABMES, and Department of Cardiology, Tokyo Women's Medical University. He received his PhD in medicine from Tokyo Women's Medical University. His areas of expertise are cardiology, regenerative medicine, stem cell biology for scale-up and tissue engineering. He has received Young Investigator's Award, The Japanese Circulation Society (2005); Inoue Memorial Foundation Research Award, Inoue Research Foundation (2007); Yamakawa Hisako Research Award, Tokyo Women's Medical University (2008); and poster award, Molecular Cardiovascular Conference (2007 and 2008). His current research interests are stem cell expansion biology and technology and cellular sociology in bioengineered tissue.