Saumya Patel, S.Prasanth Kumar, Yogesh T. Jasrai

Broschiertes Buch

Molecular Optimization of Calcineurin Inhibitors for Prion Disease

A Pharmacophore Study

Beschreibung

This study mainly emphasizes on pharmacophore features available in the immunosuppressant drugs, especially Calcineurin inhibitors for human prion diseases. The structural and functional properties of FK506/Tacrolimus - a drug used for treatment of human prion diseases were enhanced through pharmacophore-assisted molecular optimization approach. Important pharmacophore features responsible for interaction with active site and intramolecular structural stability were elucidated.

Autor

Saumya K. Patel, a budding Bioinformatician engaged in development of antimalarial and anticancer compounds and proves its efficacy in wet-lab experiments. He chosen his career in Ph.D. Bioinformatics after the completion of graduation in Biochemistry and post-graduation in Bioinformatics.He has also published research articles in reputed journals.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 80
• Englisch
• ISBN-13: 9783659158957
• ISBN-10: 365915895X
• Artikelnr.: 36018756