Molecular Dynamics of Non-Structural Proteins of Hepatitis C Virus
Gargi Tiwari
Broschiertes Buch

Molecular Dynamics of Non-Structural Proteins of Hepatitis C Virus

Versandkostenfrei!
Versandfertig in 1-2 Wochen
47,99 €
inkl. MwSt.
PAYBACK Punkte
24 °P sammeln!
There are no vaccines available against HCV and existing therapy with pegylated interferon- and ribavirin shows only 50% efficiency. It is expensive and poorly tolerated. The non-structural protein of HCV (NS5B) is thought to be responsible for replication of the viral genome. The nucleotide drug sofosbuvir is also approved for combinational treatment of chronic HCV. For the development of new non-nucleotide inhibitors it is necessary to catalogue all the available and experimentally tested drugs along with their IC50 values. Here, the most active drugs are filtered and their structures are co...