Modeling Cancer Progression on the Pathway Level
Elena Edelman
Broschiertes Buch

Modeling Cancer Progression on the Pathway Level

Assessing Cancer Progression via Pathway Dependencies

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Over the past several decades, many genes have been discovered that govern important function in the development of a variety of different cancers. However, biological insight from the list of genes is still limited and the underlying mechanisms that occur in the cell during tumorigenesis have not been well established. Studying cancer progression in terms of the oncogenic pathways that are responsible for specific actions that change normal cells into tumors is a means for bringing insight onto these issues. The work presented here will uncover mechanisms that are occurring at the pathway lev...