Modeling and Optimization of Protein Expression
Reza Gheshlaghi
Broschiertes Buch

Modeling and Optimization of Protein Expression

Statistical Methods and Metabolic Flux Analysis for Optimization of Recombinant Protein Production by Fungal Platforms

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Scientific methods of enhancing gene expression including genomics, applied molecular biology, metabolic engineering, and combinatorial biosynthesis have been sufficiently developed to make a major impact on recombinant protein production. However, it appears that the combination of trial-and-error experimentation and molecular biology are not sufficient to design an optimum strategy to reach the goal. This book provides a thorough coverage of theoretical and design aspects of two engineering methodologies to overcome this shortcoming. Special emphasis was placed on the effect of the fermentat...