Model Systems in Aging

Model Systems in Aging

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Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and humans, allowi...