Medicinal Chemistry

A Look at How Drugs Are Discovered

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The book desribes the drug discovery process, from advancing an intial lead to the approval process, and also includes sources from where drugs are discovered.

A. K. Ganguly Born in India, Prof. A. K. Ganguly was educated partly in India and in England. He attended the Imperial College of Science and Technology, London, where he obtained his Ph.D. in chemistry in 1961 under the supervision of Sir Derek Barton, a Nobel Laureate in chemistry, After finishing his studies at the Imperial College Prof. Ganguly returned back to India to work for Glaxo Laboratories and later with the Ciba Research Center in Bombay. He immigrated to the USA in 1967 and after a brief stay at the Research Institute of Medicine and Chemistry, Cambridge, Massachusetts he joined Schering Plough Research Institute, Kenilworth, New Jersey in 1968 as a Senior Scientist and where he advanced to the position of Senior Vice President of Chemical Research. He is associated with the discovery of Zetia, Posaconazole, Lonafarnib and Boceprevir. He is a coauthor of 222 papers and a coinventor of 88 patents. He has received several awards including the E.B. Hershberg award for important discoveries in Medicinal Chemistry from the American Chemical Society. After retiring from Schering-Plough, he joined Stevens Institute of Technology, Hoboken, NJ as a Distinguished Research Professor of Chemistry and presently he continues to consult in the drug discovery area. 　 Sesha Sridevi Alluri Dr. Sesha Alluri received her M.Sc. degree in medicinal chemistry in India and after working as a Senior Chemist at the Dr. Redddy's Laboratories for a few years she immigrated to the United States and joined Stevens Institute of Technology, Hoboken, New Jersey. She received a second M.S degree and Ph.D. from the institute under the supervision of Prof. A. K. Ganguly. Presently, she is working as a Lecturer in the department of Chemistry and Chemical Biology at the Stevens Institute. She teaches undergraduate and graduate chemistry courses, including medicinal chemistry and also supervises undergraduate students in organic synthesis research projects. She is the recipient of several awards including the ACS/WCC/Eli Lilly award in 2012.