Mathematical Modeling of Evolution
Igor M. Rouzine
Gebundenes Buch

Mathematical Modeling of Evolution

Volume 1: One-Locus and Multi-Locus Theory and Recombination

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The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of s...