Material Science and Biopharmaceutical Impurity Aspects
The manufacturing and purification process: a toxicological point of view
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In literature is reported that after the manifacturing or purification process of different biopharmaceuticals various impurity can be finded in the final products.Aim of this work is to verify some productive process and the possibility that substantia like graphene derivates as contaminant can be responsible to provide a response of the human innate immune system.Not only in Mrna VACCINE production but aslo in other biotechnological drugs.For the scope of this work some commercial products are reported to verify the composition and pharmaceutical industrial use : monoliths, chromatografic re...
In literature is reported that after the manifacturing or purification process of different biopharmaceuticals various impurity can be finded in the final products.Aim of this work is to verify some productive process and the possibility that substantia like graphene derivates as contaminant can be responsible to provide a response of the human innate immune system.Not only in Mrna VACCINE production but aslo in other biotechnological drugs.For the scope of this work some commercial products are reported to verify the composition and pharmaceutical industrial use : monoliths, chromatografic resins and magnetic beads .A cause effect relationship between of the reported product used in purification of biomolecule and its impurities is not the main focus of this research work but only useful to submitt to the researcher an hypotesys of impurity cause to be deeply investigated.Some commercial products are reported only to show some peculiarity.
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