Broschiertes Buch

Malonyl-CoA

Coenzyme A, Polyketide, alpha-Ketoglutaric acid, Acetyl-CoA, Acetyl-CoA carboxylase

Herausgegeben: Victorino, Terrence James

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Malonyl-CoA is a coenzyme A derivative. It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis. Malonyl-CoA is also used in transporting alpha-ketoglutarate across the mitochondrial membrane into the mitochondrial matrix. In the former, it provides 2-carbon units to fatty acids and commits them to fatty acid chain synthesis. Malonyl-CoA is formed by carboxylating acetyl-CoA using the enzyme acetyl-CoA carboxylase.