Machine Learning-Driven Rational Design in Nanomedicine

Machine Learning-Driven Rational Design in Nanomedicine

Advances in Computational Drug Delivery and In Silico Screening

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Erscheint vorauss. 21. November 2025
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This book explores how machine learning is transforming nanomedicine, with a focus on the rational design of lipid nanoparticles (LNPs) for mRNA-based therapies. Moving beyond traditional, labor-intensive workflows, it highlights AI-driven methods-such as supervised learning, data augmentation, and deep learning-for predictive modeling and in silico screening. Key topics include chemoinformatics, molecular fingerprinting, and strategies to optimize LNP transfection efficiency and biocompatibility. Real-world applications, including mRNA vaccines and personalized nanomedicines, illustrate the c...