Linear morphs
Epidemioclinical, therapeutic and evolutionary profile at Hôpital Charles Nicolle in Tunis
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The study retrospectively examined 18 cases of linear morphea (ML), a rare skin disease, at Charles Nicolle Hospital between 2000 and 2015.MLs predominantly affected women (M/F sex ratio 0.63) and young people (mean age 14.94). Most lesions are located on the limbs. Joint involvement, such as arthralgia, was the most frequent extracutaneous complication.Initial treatment consisted of corticosteroids, but more effective management was achieved with methotrexate (MTX). Prognosis is generally good, despite possible cosmetic sequelae. However, complications (bone and joint damage, diabetes) and re...
The study retrospectively examined 18 cases of linear morphea (ML), a rare skin disease, at Charles Nicolle Hospital between 2000 and 2015.MLs predominantly affected women (M/F sex ratio 0.63) and young people (mean age 14.94). Most lesions are located on the limbs. Joint involvement, such as arthralgia, was the most frequent extracutaneous complication.Initial treatment consisted of corticosteroids, but more effective management was achieved with methotrexate (MTX). Prognosis is generally good, despite possible cosmetic sequelae. However, complications (bone and joint damage, diabetes) and recurrences have been observed in some patients.The study, limited by its retrospective and monocentric nature, underlines the importance of treatment combining corticosteroids and MTX, in line with the recommendations of the Childhood Arthritis and Rheumatology Research Alliance (CARRA).
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