KineticStudy of Diclofenac Sodium from MethocelK15MCR and Cetylalcohol

KineticStudy of Diclofenac Sodium from MethocelK15MCR and Cetylalcohol

Using Model dependent and Independent Methods and Bioequivalence Study

Versandkostenfrei!
Versandfertig in 6-10 Tagen
32,99 €
inkl. MwSt.
PAYBACK Punkte
16 °P sammeln!
Current study aimed at the development of a matrix type sustain release Diclofenac tablet, using hydrophilic HPMC and hydrophobic polymer Cetyl alcohol. It was found that hydrophilic Methocel K15 MCR® matrices based tablets showed zero order and hydrophobic cetyl alcohol matrices based tablets were followed first-order kinetics except formulation six (F6 showed zero order profile). The result of dissolution study indicated that formulations containing cetyl alcohol showed better dissolution properties as compared to formulations containing Methocel K15 MCR® in terms of similarity and differe...