Kinase Inhibitors
Poonam Kaswan
Broschiertes Buch

Kinase Inhibitors

An Overview

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One of the most significant targets of drugs in the 21st century is the family of protein kinase enzymes. There are 62 therapeutic agents authorized by FDA, which target about two dozen distinct proteins. Except for Netarsudil, which is used to treat optical eyes and temsirolimus for renal cell carzinoma, all the FDA-approved medications are orally safe. Key common targets of the medicinal product include BCR-Abl, B-Raf, vascular receptors, VEGFR, and EGFR, as well as ALK. The following are 8 approved drugs of 2020 approved-Tucatinib, Ripretinib, Selumetinib, Capmatinib, Pemigatinib Pralsetini...