Investigation of solid-state diversity of Amantadine Hydrochloride

Investigation of solid-state diversity of Amantadine Hydrochloride

Investigation of Amantadine HCl

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The aim of this work was to study the different solid forms of Amantadine hydrochloride, possible co-crystals, produce new solid forms by using different selected solvents to produce new solid forms and diffraction quality crystals analyse the structure determine at where possible. By using different sophisticated equipment, methodology concluded that the new polymeric form such as SXD-Single Crystal X-ray Diffractions , PXRD- Powder X-ray Diffraction, DSC- Differential Scanning Calorimetry, STA-Simultaneous Thermal Analysis, TG-Thermo Gravimetric Analysis., VTPXRD-Variable Temperature Powder ...