Infective Free Supermitochondria - Archaeal RNA Viroid Hybrids
Role in Mitochondrial Dysfunction, Mitoinflammation and Cell Death
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Supermitochondria formed by hybridization of mitochondrial RNA and archaeal RNA viroids makes the mitochondria dysfunctional and produces a mitochondrial disorder with a mitoinflammatory state leading to mitochondrial caspase mediated cell death. The infected supermitochondria can act like a bug and can be transferred during sexual intercourse as the male mitochondrial genome contributes to the embryonic mitochondrial genome also.
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