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Why haven't we already eliminated tuberculosis (TB)? Why does it continue to plague the globe, contributing to the greatest burden of disease than any other single pathogen? While a substantial body of literature focuses on the challenging social determinants, including low economic development and HIV, that are associated with TB prevalence, this book focuses on an active and hopeful framework for TB elimination. Here, the manifestation of the social determinants toward TB's persistence is explained by the mechanics of TB transmission, opening a powerful and clear pathway for systematic global TB control. As an obligate airborne pathogen, TB only spreads through the air between humans. This collection describes the key elements of early detection and diagnosis that are helpful for all students of TB and practitioners implementing TB control in the field. The collection is also beneficial for policymakers interested to quickly learn more about TB in support of policies and funding efforts to truly make meaningful progress and achieve TB elimination. This work is not simply food for thought. Despite the preventable and controllable nature of TB, TB takes over a million lives each year. While new vaccines are on the horizon and can help, we already have all the tools we need to eliminate TB. It's time to direct focus on a focused effort of implementation.