Immunofluorescence in Oral Lesion

Immunofluorescence in Oral Lesion

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Immunofluorescence is an immunohistochemical method used to demonstrate the presence of antigen and antibodies in the tissues or serum. It is an auxiliary diagnostic tool for the autoimmune bullous and inflammatory disorders. It detects the in situ and circulating immune deposits that are involved in the pathogenesis of immunobullous diseases. Immunobullous group of disorders is characterized by the production of antibodies that are directed against various constituents of the molecular apparatus that hold the epithelial cells together or that bind the surface of the epithelium to the underlyi...