Hyperfiltration in arterial hypertension
Prevalence, clinical significance, ways of correction
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In Russia, 40% of the population suffers from AH and its share in the formation of nephrosclerosis and UTI is constantly increasing. There is a clear need to identify the early stages of renal damage. Hyperfiltration (HF) leads to the development of IAH and is a marker of metabolic risk. Due to the lack of data on the prevalence of HF in Russia and unsolved problem of the choice of medical treatment in patients with AH and HF, the present work was carried out to study the prevalence of HF and evaluate correlation between HF and the main clinical and laboratory parameters based on the analysis ...
In Russia, 40% of the population suffers from AH and its share in the formation of nephrosclerosis and UTI is constantly increasing. There is a clear need to identify the early stages of renal damage. Hyperfiltration (HF) leads to the development of IAH and is a marker of metabolic risk. Due to the lack of data on the prevalence of HF in Russia and unsolved problem of the choice of medical treatment in patients with AH and HF, the present work was carried out to study the prevalence of HF and evaluate correlation between HF and the main clinical and laboratory parameters based on the analysis of over 2000 case reports. The dynamics of the severity of systemic inflammation, BP in patients with GF against the background of treatment with AAP or ARA was studied, and the nephroprotective effect of these classes of drugs was evaluated and compared. The correlation between central BP, pulse wave velocity and augmentation index, measured by applanation tonometry, with GF level, and their dynamics during treatment with ADF or ARA was studied. The quality of life in AH patients with HF during treatment with the SF-36 questionnaire was assessed. The book is relevant for general practitioners, cardiologists, who daily face the problem of kidney damage in AH.
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