Broschiertes Buch

Histone Modifications in Therapy

Volume 20

Herausgegeben: Castelo-Branco, Pedro; Jeronimo, Carmen

Beschreibung

Histone Modifications in Therapy provides an in-depth analysis of the role of histone mechanisms in major diseases and the promise of targeting histone modifications for disease prevention and treatment. Here, researchers, clinicians and students will discover a thorough, evidence-based discussion of the biology of histones, the diseases engaged by aberrant histone modifications, and pathways with therapeutic potential. Expert chapter addresses the role of histone modifications across a variety of disorders, including cancer, neuropsychiatric, neurodegenerative, cardiac, metabolic, infectious, bacterial, autoimmune and inflammatory disorders, among others. In relation to these disease types, histone modifications are discussed, both as mechanisms of prevention and possible treatment.

A concluding chapter brings together future perspectives for targeting histone modifications in therapy and next steps in research.

Autor

Pedro Castelo Branco completed his doctorate in molecular biology at Oxford University in 2005, followed by post-doctoral fellowships at Harvard University and the University of Toronto. Since 2014 he is a Professor in the Department of Biomedical Sciences and Medicine and head of the Epigenetics in Human Disease laboratory , at the University of the Algarve. His scientific interests include the identification of specific epigenetic signatures throughout carcinogenesis and targeted methylation/demethylation as a therapeutic approach.

Produktdetails

• Translational Epigenetics Volume 20
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: C2018-0-00075-4
• Seitenzahl: 490
• Erscheinungstermin: 21. August 2020
• Englisch
• Abmessung: 23mm x 191mm x 235mm
• Gewicht: 1020g
• ISBN-13: 9780128164228
• ISBN-10: 0128164220
• Artikelnr.: 58567715