High-Selective Stationary Phases for Liquid Chromatography
Design, synthesis, characterization, and application of high-selective stationary phases
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High-selective high-performance liquid chromatographic (HPLC) stationary phases are needed to separate certain classes of isomers that are important in the disciplines of environmental, pharmaceutical, clinical, and food sciences. However, their separation is challenging for the analyst due to similar polarity and structural similarity of the compounds. To solve this problem, the integration with ordered arrangement of functional groups in an organic phase on silica is a very useful strategy, which enhance the selectivity in HPLC: well-oriented subsidiary weak interaction sites are the driving...
High-selective high-performance liquid chromatographic (HPLC) stationary phases are needed to separate certain classes of isomers that are important in the disciplines of environmental, pharmaceutical, clinical, and food sciences. However, their separation is challenging for the analyst due to similar polarity and structural similarity of the compounds. To solve this problem, the integration with ordered arrangement of functional groups in an organic phase on silica is a very useful strategy, which enhance the selectivity in HPLC: well-oriented subsidiary weak interaction sites are the driving force for the separation of very complex component mixtures. Polymer-grafted silica stationary phase is one of the best ways to realize these requirements (including atom transfer radical polymerization, ATRP). This book, therefore, provides the design, synthesis, characterization of novel stationary phases by changing polymerization techniques, spacer lengths, monomer sets and their chromatographic to solve these separation challenges. The book should be especially useful to professionals in Analytical and Chromatography fields
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