Hepatic Fibrosis: Mechanisms and Therapies
Gebundenes Buch

Hepatic Fibrosis: Mechanisms and Therapies

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Hepatic fibrosis is characterized by the scarring, overgrowth and hardening of different tissues of the liver and is caused by an excess buildup of extracellular matrix components such as collagen. It is the result of repeated wound-healing response of the liver to repeated injuries. It can be caused due to chronic liver diseases such as cystic fibrosis (CF), hepatitis B and hepatitis C. Cystic fibrosis refers to a type of inherited disease characterized by the accumulation of thick and sticky mucus that can harm many organs of the body. CF may lead to hepatic fibrosis, by causing mucus build ...