Helicobacter pylori
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Helicobacter pylori

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The revolutionary discovery of Helicobacter pylori started a new era in the understanding and management of gastroduodenal diseases. H. pylori is associated with chronic gastritis, peptic ulcers, MALT lymphoma, the pathogenesis of gastric cancer and several extra-gastric diseases. The organism displays an enormous genetic diversity and some strains harbour numerous virulence factors. No vaccines are available yet and increased antibiotic resistance of the bacteria is of growing concern. Many questions about H. pylori pathogenesis, epidemiology, prophylaxis and treatment remain to be answered. ...