Heat Shock
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During the last years the heat shock response has been stu-died as a model system to analyze control mechanisms regula-ting the synthesis of heat shock proteins providing impor-tant general insight into the regulation of gene expression.But the major revelation, which has sparked interest fromall quarters of biology, is the discovery that heat shockproteins play major roles in an extraordinary variety ofnormal cellular processes. They are the focus of investiga-tions in many areas of cell biology, including protein traf-ficking, signal transduction, DNS replication, transcrip-tion, protein syn...
During the last years the heat shock response has been stu-
died as a model system to analyze control mechanisms regula-
ting the synthesis of heat shock proteins providing impor-
tant general insight into the regulation of gene expression.
But the major revelation, which has sparked interest from
all quarters of biology, is the discovery that heat shock
proteins play major roles in an extraordinary variety of
normal cellular processes. They are the focus of investiga-
tions in many areas of cell biology, including protein traf-
ficking, signal transduction, DNS replication, transcrip-
tion, protein synthesis, and in the assembly of di- verse
protein structures. These aspects are thoroughly trea- ted
in the book, as are the implications in immunology, in- fec-
tious diseases, chronic degeneration, hyperthermia, and can-
cer research.
died as a model system to analyze control mechanisms regula-
ting the synthesis of heat shock proteins providing impor-
tant general insight into the regulation of gene expression.
But the major revelation, which has sparked interest from
all quarters of biology, is the discovery that heat shock
proteins play major roles in an extraordinary variety of
normal cellular processes. They are the focus of investiga-
tions in many areas of cell biology, including protein traf-
ficking, signal transduction, DNS replication, transcrip-
tion, protein synthesis, and in the assembly of di- verse
protein structures. These aspects are thoroughly trea- ted
in the book, as are the implications in immunology, in- fec-
tious diseases, chronic degeneration, hyperthermia, and can-
cer research.
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