Abel Lajtha (ed.-in-chief)

Gebundenes Buch

Handbook of Neurochemistry and Molecular Neurobiology

Neuroimmunology

Herausgegeben: Lajtha, Abel; Lajtha, Abel, Herausgegeben: Galoyan, Armen

Beschreibung

This volume contains data on multiple immunomodulators, many of which are also the products of hypothalamic brain cell neurosecretion. Interleukins (IL-1a, IL-1ß, IL-2, IL-4, IL-6, TNFa), immunophylin and ubiquitin as well as proline rich peptides, comprised of 10-15 amino acids are being produced in N. Supraopticus and N. Paraventricularis and then secreted into neurohypophysis. Along the neurosecretion of the mentioned cytokines, there are other immunomodulators, the primary structure of which had been completely deciphered such as: Immunophyllins, intracellular receptors of immunosuppressors FK506, cyclosporine A., rapamicin. They are peptidyl-prolyl-cis-trans-isomerases. There are novel immunological hypothalamic factors such as ubiquitin, macrophage migration inhibitory factor (MIF), as well as Thymosin ß 4(1-39). This data allowed us to propose the concept of neuroendocrine immune system of the brain.

Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 11417729, 978-0-387-30358-1
• 3rd ed.
• Seitenzahl: 512
• Erscheinungstermin: 14. Dezember 2007
• Englisch
• Abmessung: 250mm x 175mm x 33mm
• Gewicht: 991g
• ISBN-13: 9780387303581
• ISBN-10: 0387303588
• Artikelnr.: 23155087

Rezensionen

From the reviews of the third edition:

"A new edition of the Handbook of Neurochemistry and Molecular Neurobiology has now been issued in 25 volumes. It contains fundamental data on current molecular neurobiology, neuroimmunology, and neuropathology. This is the first time that the series contain Neuroimmunology, which summarizes achievements in neurochemistry, neuroendocrinology, neurophysiology, and the pathology of the nervous system. ... This book presents research performed by scientists in various countries. ... a handbook for scientists, students, and clinicians." (K. G. Gevorgyan, Neurochemical Journal, Vol. 3 (1), 2009)