Ajit P Ingale, Sandeep V Shinde

Broschiertes Buch

Green Methodology

Green Protocol for synthesis of Pyarzole, Nitriles and N-tert-butylcarbamate, Quinoxalines

Beschreibung

The present research work is divided into four chapters which mainly focusing on the development and application of novel protocols for the synthesis of various functionalized aryl nitriles, N-Boc protected amines, pyrazoles and quinoxalines. The first chapter deals with Catalyst-free, efficient and one pot protocol for synthesis of nitriles from aldehydes using glycerol as green solvent. This protocol was efficiently used for transformation of aromatic aldehydes bearing electron-withdrawing and electron-donating groups into aryl nitriles in good to excellent yields. The methodology offers a very simple, efficient and environmentally benign procedure. The second chapter deals with Catalyst-free, highly efficient and chemoselective N-tert-butyloxycarbonylation of amines in green solvent glycerol. The varieties of functionalized amines such as aliphatic, aromatic as well as heteroaromatic were protected by using developed protocol. The third chapter deals with Iodine promoted efficient synthesis of 3,5-Disubstituted 1H-pyrazoles from acetophenone hydrazone and substituted aldehydes. This practical one-pot protocol is metal-free and requires no isolation of less stable intermediate.

Autor

Dr. Ajit Ingale has received his M.Sc. degree from SPPU, Pune and doctorate degree in Organic Chemistry from SRTM University, Nanded, India. He is working as an Assistant Professor in the Department of Chemistry, Dada Patil College, Karjat, India. His area of research is the synthesis of organic compounds by using green solvents & green catalysts 

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 200
• Erscheinungstermin: 7. Oktober 2021
• Englisch
• Abmessung: 220mm x 150mm x 12mm
• Gewicht: 316g
• ISBN-13: 9786204209616
• ISBN-10: 6204209612
• Artikelnr.: 62864418