Glimpse into an ATP synthase's F0 motor at work
Alexander Wiedenmann
Broschiertes Buch

Glimpse into an ATP synthase's F0 motor at work

Requirements for torque generation in proton and sodium dependent F-type ATP synthases

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The majority of ATP, the carrier of energy in the living world, is generated by the ATP synthase. The enzyme complex converts energy from the transmembrane electrochemical gradient into rotation by an H+ or Na+ current through the F0 part. The rotation is transmitted to the F1 part, where ATP is formed from ADP and Pi. The present thesis aimed to elucidate the requirements for torque generation during ATP synthesis in the holoenzyme as well as in the isolated F0 part. To achieve this, a quantitative H+ transport assay was established. Furthermore, the Na+-dependent enzyme from P. modestum and ...