Genetic Changes and Their Prognostic Impact In Leukaemia Patients

Genetic Changes and Their Prognostic Impact In Leukaemia Patients

Characterization of Cytogenetic and Molecular Genetic Changes and Their Prognostic impact in Acute Leukaemia Patients

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In Pakistan comprehensive data from population based studies on the incidence of childhood leukaemia is generally lacking. In developing countries, treatment of acute lymphoblastic leukaemia (ALL) usually relies on different immunophenotypic, cytogenetic and molecular subsets that have differing outcomes with different therapies. In Pakistan, treatment offered to patients is usually based on clinical features of disease at presentation. This book attempts to identify and characterize different risk factors and clinical and genetic prognostic markers in Pakistan ALL patients.Moreover, classific...