Gene expression analysis in diffuse large B-cell lymphoma
Helena Hauge
Broschiertes Buch

Gene expression analysis in diffuse large B-cell lymphoma

Identification and characterization of novel proteins

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Follicular lymphoma (FL) represents the most common low-grade Non-Hodgkin's lymphoma. FLs are of B cell origin, generally incurable, and frequently transform to high-grade diffuse large B cell lymphoma (DLBCL). Transformation is generally correlated with poor prognosis and the molecular mechanisms involved are largely unknown. This book gives an introduction to the field of carcinogenesis with focus on the events leading to Non-Hodgkin's lymphoma and presents the results of a study aimed at identifying novel genes differentially expressed in patient-matched biopsies of FL and DLBCL to increase...