Fundamentals of Neurodegeneration and Protein Misfolding Disorders
Martin Beckerman
Broschiertes Buch

Fundamentals of Neurodegeneration and Protein Misfolding Disorders

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This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on multiple fronts. These findings provide novel insights on how amyloidogenic oligomers and fibrils form, interconvert from one state to another, and propagate from cell to cell and region to region. Starting with protein folding and protein quality control b...