Formulation of Thymoquinone Nanoparticles and its in-vitro Evaluation
Sanjar Alam
Broschiertes Buch

Formulation of Thymoquinone Nanoparticles and its in-vitro Evaluation

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Hydrophobic drugs delivered orally encounter permeabil ity problems and hence poor bioavailability. They undergo chemical and enzymatic degradation in the gastrointestinal tract and show extensive hepatic first-pass metabolism. Similarly, various additional factors hinder drug discovery and the development of an effective delivery of different therapeutic molecules. Thymoquinone (THQ) a major active lipophilic component of Nigella Sativa (Ranunculaceae) was reported to have many pharmacological qualities such as its immu-nomodulation, anticancer, anti-inflammatory and antioxidant effects. Phys...