Formulation and Evaluation of Olmesartan Medoxomil Dry Emulsion

Formulation and Evaluation of Olmesartan Medoxomil Dry Emulsion

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In this book, the dry emulsion of Olmesartan medoxomil is prepared by spray drying method to improve the dissolution of poorly water soluble drug. Olmesartan medoxomil is a poorly soluble drug useful in the treatment of hypertension, absorption window of drug is stomach and upper part of small intestine.Dry emulsions can be prepared by spray drying, lyophilization and rotary evaporation. Dry emulsion was prepared by using castor oil in which drug is highly soluble, poloxamer188 as water soluble carrier and aerosil 200 as an adsorbent. The preferred oil was castor oil, olive oil, soybean oil an...