Formulation and Development of Cefixime Trihydrate Floating Tablets
Binapani Barik
Broschiertes Buch

Formulation and Development of Cefixime Trihydrate Floating Tablets

Cefixime trihydrate floating tablets for the treatment of peptic ulcer

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The purpose of this research is to develop the hydro-dynamically balanced delivery system of Cefixime Trihydrate for the localized action in the stomach, in the treatment of H.pylori mediated peptic ulcer. By applying wet granulation technique floating tablets of cefixime trihydra is prepare. Drug-Excipient compatibility study is performed by FTIR and DSC .Eudragit RS 100 polymer is use for maintaining drug release, % drug release, floating lag time and swelling index. The formulation developed using Cefixime trihydrate, Eudragit RS100, sodium bicarbonate gave floating lag time with a floating...