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Formulation & Development of Floating Drug Delivery System

Formulation, Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Anti-platelet Drug - Second Edition

Herausgeber: Sharma, Gaurav Kumar

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From above experimental findings it can be concluded that: ¿ Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. ¿ The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. ¿ The mechanism of drug release was found to be matrix diffusion controlled. ¿ Formulations showed satisfactory results from Stability studies. ¿ Further in-vivo investigations are necessary to correlate in-vitro data.