Formulation & Development of Floating Drug Delivery System

Formulation & Development of Floating Drug Delivery System

Formulation, Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Anti-platelet Drug

Herausgegeben: Sharma, Gaurav Kumar
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From above experimental findings it can be concluded that: - Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. - The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. - The mechanism of drug release was found to be matrix diffusion controlled. - Formulations showed satisfactory results from Stability studies. - Further in-vivo investigations are necessary to correlate in-vitro data.