Fluorescent Membrane Probes for Apoptosis and Raft Domains
Oleksandr Kucherak
Broschiertes Buch

Fluorescent Membrane Probes for Apoptosis and Raft Domains

Design, Synthesis and Application

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Fluorescent dyes are of great importance for investigation of biological processes. In 2007 the first ratiometric fluorescent probe for apoptosis detection (F2N12S) has been reported. This book is focused on a development of the improved analogs of F2N12S. Firstly, the systematic studies of F2N12S in model membranes and cells are described for better understanding of its mechanism of response to apoptosis. Secondly, synthesis of new membrane probes is presented. All the molecules are classified into three types according to their sensitivity profiles (sensitive both to the surface charge and t...