Extrusion-Spheronization VS Solution / Suspension Layering Technique
Prateek Kulshrestha
Broschiertes Buch

Extrusion-Spheronization VS Solution / Suspension Layering Technique

for Formulation of Itopride Hydrochloride Pellets: A Truce

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Purpose: The purpose of this study is to formulate itopride hydrochloride sustained release pellets by Extrusion-Spheronization and Solution/ Suspension layering technique and to compare the pellet characteristics prepared from both the techniques. Methods: In the Extrusion-Spheronization technique, the drug pellets were prepared by mixing the drug with excipients along with a binder solution, the resultant mass was extruded through extruder followed by spheronizer. In Solution/suspension layering technology the pellets were prepared by coating the drug solution/suspension on the sugar spheres...